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Little degradation (apparent t1/2 about 10 h) of DSIP to major metabolites, tryptophan (trp) and des-trp DSIP, occurred over the time of the diffusion experiments

Of course, the vitamin B12 shots themselves do not stay in the body for five years

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Researchers select format based on route of administration requirements and whether the protocol calls for fixed or variable dosing across experimental arms

The length of the infusion is also important

doi: 10.1186/s12890-021-01575-7 128 ieMRSue-ChuMHelvikASSteinsvagSKSteinsbekkSThorstensenWM